You need to enable JavaScript to use the communication tool powered by OpenWidget
Ketamine for Depression — Santa Monica, CA

Depression Treatment in Santa Monica That Actually Works.

Golden Afternoon is Santa Monica’s physician-designed ketamine clinic — offering IV ketamine and Spravato® for treatment-resistant depression and major depressive disorder. Rapid relief, all 5-star reviews, right here at 1450 10th Street.

Book a Free Phone Screening
✦ Santa Monica, CA✦ IV Ketamine & Spravato®✦ MD-Designed Protocols✦ All 5-Star Reviews
The Science

How Ketamine Treats Depression in Santa Monica

Golden Afternoon offers the two most clinically effective ketamine-based treatments for depression available today — IV ketamine and Spravato® (esketamine). Both work by targeting the brain’s glutamate system and promoting rapid neuroplasticity, often producing meaningful relief within hours to days of the first treatment.

For Santa Monica patients who have tried medications or therapy without success, this speed of response can be genuinely life-changing — and both options are available at our clinic on 10th Street.

Works Rapidly

Many patients notice significant relief within hours to days — far faster than SSRIs and SNRIs which can take weeks.

Works Differently

Ketamine rebuilds neural pathways that depression erodes. It’s not just symptom management — it’s neural repair.

Clinically Proven

Decades of research support ketamine’s efficacy for treatment-resistant depression and major depressive disorder.

Your Options

IV Ketamine or Spravato® — Both in Santa Monica

Dr. Jenn will help determine the right treatment for your diagnosis, history, and insurance during your free screening.

Self-Pay + Superbill

IV Ketamine Infusion

The gold standard. Precise intravenous delivery with real-time dosing adjustments. Most patients do 6 infusions over 2–3 weeks. Treats depression, anxiety, PTSD, and chronic pain.

IV Ketamine Santa Monica →
Often Insurance-Covered

Spravato® (Esketamine)

FDA-approved nasal ketamine for treatment-resistant depression and MDD. Often covered by insurance for qualifying patients. Administered in-clinic with required 2-hour monitoring. Typically twice weekly for 4 weeks.

Spravato Santa Monica →
How It Works

Getting Started with Depression Treatment in Santa Monica

From your first call to your ongoing maintenance plan, we walk with you every step of the way.

01

Free Phone Screening

A no-cost, no-pressure 15-minute call. We’ll discuss your depression history and determine whether IV ketamine or Spravato® is right for you.

02

Your First Session

Our care team works with you before and after your first infusion — setting your intention, ensuring comfort, helping you contextualize the experience. Dr. Jenn designed every step.

03

Your Treatment Plan

Most patients do 6 IV infusions over 2–3 weeks, or twice-weekly Spravato® for a month. Dr. Jenn then builds a personalized maintenance plan to protect your results long-term.

Patient Stories

Santa Monica Patients. Real Relief from Depression.

All 5-star reviews across Google, Yelp, and Reddit.

★★★★★

“The results of her care have reshaped my view on family, work and play where all other courses of treatment for depression and anxiety haven’t made a dent. Go here.”

Peter H. — Google
★★★★★

“This was a life-altering experience. I can’t say enough or fully articulate what a truly safe, healing experience this was. Everyone in the world needs this!”

Kyla B. — Yelp
★★★★★

“Golden Afternoon in Santa Monica 1000% — the doctor is FANTASTIC. Fully private rooms, never busy. Golden Afternoon is the absolute best.”

TheGaymerOtter — Reddit
★★★★★

“My life has changed for the better because of them. I would highly encourage anyone looking for ketamine treatments to choose Golden Afternoon.”

Robert L. — Google

Relief from Depression Is a Phone Call Away.

A free 15-minute screening with our Santa Monica care team is all it takes to get started. No pressure, no commitment — just a real conversation about whether ketamine therapy is right for you.

Book Your Free Phone Screening

Call 310-310-8031  ·  1450 10th St, Suite 300, Santa Monica, CA