If you’ve tried everything for chronic pain and still aren’t finding relief, IV ketamine infusion therapy may be the answer. Golden Afternoon offers fully customized, physician-designed ketamine treatment plans — built around your specific condition, not a one-size-fits-all protocol.
Book a Free Phone ScreeningChronic pain is not just a symptom — it is a condition in the nervous system itself. Over time, persistent pain causes changes in the spinal cord and brain that amplify pain signals, a process called central sensitization. This is why chronic pain so often continues long after the original injury or cause has resolved, and why conventional pain medications provide limited or diminishing relief.
IV ketamine works by blocking NMDA receptors — a key driver of central sensitization — and by promoting neuroplasticity that can help reset overactive pain pathways. It has shown meaningful clinical benefit for conditions including complex regional pain syndrome (CRPS), fibromyalgia, neuropathic pain, failed back surgery syndrome, chronic migraines, and more.
By blocking NMDA receptors involved in central sensitization, ketamine can interrupt the amplified pain signals that make chronic pain feel inescapable — providing relief that other treatments cannot.
Chronic pain protocols typically use longer infusion times than mood disorder treatments. Dr. Jenn will design a plan calibrated to your condition, history, and goals — not a template.
Intravenous delivery allows for exact, real-time dosing adjustments throughout your infusion — essential for chronic pain patients, where the therapeutic window can differ significantly from person to person.
IV ketamine has shown clinical benefit across a wide range of chronic pain conditions. If you don’t see yours listed, reach out — Dr. Jenn will evaluate whether ketamine may be appropriate for your situation.
Chronic pain ketamine protocols are meaningfully different from those for depression or anxiety. Infusions are often longer — sometimes several hours — and the number of sessions, dosing, and spacing are all calibrated to your specific condition and response.
Dr. Jenn will personally review your history and design a custom protocol for you before your first infusion. There is no standard template for chronic pain — every plan is built from scratch around you.
Your diagnosis — CRPS, fibromyalgia, neuropathic pain, and others each have different evidence-based protocols
Infusion duration — chronic pain infusions are often longer than mood disorder infusions, sometimes 3–4+ hours
Number of sessions — typically a series of infusions, with maintenance planned based on your response
Your medication history — prior treatments, current medications, and tolerance all inform the protocol
Chronic pain patients have often been through the medical system many times over. We understand that. Golden Afternoon is designed to be different — unhurried, attentive, and built around your individual picture.
Dr. Jenn personally reviews every chronic pain patient’s history and builds a custom ketamine protocol before your first infusion. Our experienced care team — including trained Nurse Practitioners — then executes that plan with the same standards she sets.
Chronic pain infusions can run several hours. Our zero-gravity infusion chairs, private rooms, curated lighting, and bespoke playlists are designed to make longer sessions as comfortable and restorative as possible.
IV ketamine allows our care team to adjust dosing in real time throughout your infusion. For chronic pain — where optimal dosing varies widely between patients — this level of control is critical to getting results.
Relief from ketamine is not always permanent, but it can be sustained. Dr. Jenn builds every patient a maintenance plan to protect and prolong the gains from their initial series of infusions.
We take a deliberate, personalized approach — because chronic pain is complex, and your treatment plan should reflect that.
Start with a no-cost call with our care team. We’ll discuss your pain history, prior treatments, and current condition to assess whether IV ketamine therapy is appropriate for your situation.
Before your first infusion, Dr. Jenn personally reviews your case and designs a custom protocol — including infusion duration, number of sessions, and dosing strategy — tailored specifically to your diagnosis and history.
Chronic pain infusions are often longer than mood disorder infusions — sometimes 3 to 4 hours or more per session. Our care team monitors you closely throughout. After your series, Dr. Jenn creates a maintenance plan to help sustain your results.
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Is ketamine approved for chronic pain?
IV ketamine is used off-label for chronic pain, supported by decades of clinical research and widespread use in academic pain centers. It is particularly well-studied for complex regional pain syndrome (CRPS), neuropathic pain, and fibromyalgia. Dr. Jenn will assess whether ketamine is clinically appropriate for your specific diagnosis during your screening.
Are chronic pain infusions different from depression or anxiety infusions?
Yes — meaningfully so. Chronic pain protocols typically involve longer infusion times, often 3 to 4 hours or more per session, compared to the shorter infusions used for mood disorders. The dosing strategy, number of sessions, and spacing are also different. Dr. Jenn designs every chronic pain patient’s protocol individually based on their diagnosis and history.
How many infusions will I need for chronic pain?
This varies by condition and individual response, and is one of the reasons Dr. Jenn creates a custom plan for every chronic pain patient. Some conditions respond well to a shorter series; others benefit from more sessions. Your plan will also include a maintenance strategy to sustain your results over time.
How long does pain relief from ketamine last?
Relief duration varies by patient and condition. Some patients experience significant relief for weeks to months after a series of infusions. Periodic booster infusions are often used to maintain results. Dr. Jenn will build a maintenance plan as part of your overall treatment protocol.
Is IV ketamine safe for chronic pain patients who are on other medications?
Safety is evaluated individually. Dr. Jenn reviews your full medication history before designing your protocol — some medications can interact with ketamine and may need to be adjusted in advance. This is why a thorough intake process is an essential part of our chronic pain program.
Does insurance cover ketamine for chronic pain?
IV ketamine for chronic pain is generally not covered by insurance, though we provide superbills for potential out-of-network reimbursement. We are happy to walk you through costs and options during your free phone screening.
A free 15-minute phone screening is the first step. Talk with our care team about your chronic pain history — no pressure, no commitment — and find out whether a custom IV ketamine protocol could help you find real relief.
Book Your Free Phone ScreeningOr call us at 310-310-8031 · Located in Santa Monica, CA
Our safe and integrative IV and intranasal Ketamine sessions can help re-wire your neurons and are a proven treatment for depression, anxiety, PTSD, mood disorders and chronic pain.
Golden Afternoon is a dba of Jennifer A Ellice MD PC
